Patient selection: celiac disease
Criteria for celiac crisis:
(1) acute onset or rapid progression of gastrointestinal symptoms secondary to celiac disease
(2) requires hospitalization and/or parenteral nutrition
(3) >= 2 clinical and laboratory findings (see below)
Clinical and laboratory findings:
(1) severe acute diarrhea with dehydration
(2) abnormal electrolyes (hypokalemia, hypocalcemia, hypomagnesemia, hyper or hyponatremia)
(3) renal dysfunction with serum creatinine > 2 mg/dL
(4) metabolic acidosis with pH < 7.35
(5) hypoalbuminemia (serum albumin < 3.0 g/dL)
(6) weight loss > 10 lbs (4.5 kg)
(7) neurologic dysfunction including paralysis
The diagnosis requires exclusion of other explanations for the acute deterioration.
