The cytoplasmic granules within a neutrophil may become larger and more prominent in sepsis or other acute reactive processes. This change is termed toxic granulations.
Parameters:
(1) size of cytoplasmic granules
(2) percent of neutrophils showing toxic granulations
Cytoplasmic Granules
Percent of Neutrophilic Cells with Toxic Granulation
Grade
all small and uniform
< 5%
0
mostly small with a few larger
< 5%
+/-
some small with some larger
5 to 25%
1+
mostly intermediate
25.1 to 50%
2+
intermediate with some large
50.1 to 75%
3+
almost all large
> 75%
4+
where:
• This may be a situation where a score determined by (size) * (percent) would be effective.
To read more or access our algorithms and calculators, please log in or register.
