Braun et al listed criteria for the diagnosis of sinonasal sarcoidosis. The authors are from Hopital de Hautepierre in Strasbourg, France.
Diagnostic criteria:
(1) presence of chronic rhinosinusitis with changes documented on imaging studies
(2) poor response to conventional therapy
(3) noncaseating granulomas identified on biopsy
(4) elevated serum angiotensin-converting enzyme (ACE)
(5) diagnosis of systemic sarcoidosis
(6) exclusion of other causes of noncaseating granulomas (Wegener’s granulomatosis, infection, etc)
Supportive evidence:
(1) presence of nodules on the septum and/or turbinates
(2) positive Gallium scan
(3) active and/or pulmonary sarcoidosis
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Specialty: Otolaryngology, Infectious Diseases, Immunology/Rheumatology
ICD-10: ,