Description

O'Donnell et al defined an exacerbation of bronchiectasis by the presence of several clinical findings. These can help to identify a patient who may benefit from more aggressive management. The authors are from Georgetown University Medical Center, Oregon Health Sciences University, Winthrop University Hospital and Genentech.


 

Clinical parameters:

(1) sputum production

(2) dyspnea

(3) cough

(4) body temperature (fever, defined as > 38°C)

(5) wheezing

(6) systemic symptoms (fatigue, malaise, lethargy, exhaustion after exertion)

(7) pulmonary function

(8) changes in chest sounds

(9) changes on chest imaging studies

Parameter

Finding

Points

sputum production

decreased or unchanged

0

 

changed (increased, purulent, hemoptysis)

1

dyspnea

decreased or unchanged

0

 

increased

1

cough

decreased or unchanged

0

 

increased

1

body temperature

decreased or unchanged

0

 

increased, > 38°C

1

wheezing

decreased or unchanged

0

 

increased

1

system symptoms

decreased or unchanged

0

 

increased

1

pulmonary function

improved or unchanged

0

 

reduced

1

chest sounds

normal or unchanged

0

 

consistent with new pulmonary process

1

chest imaging studies

normal or unchanged

0

 

consistent with new pulmonary process

1

 

number of findings =

= (number of points for all 9 parameters))

 

Interpretation:

• minimum number of findings: 0

• maximum number of findings: 9

• An acute exacerbation was defined as >= 4 findings.

 


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