Night sweats can occur with a large number of conditions. Its significance depends on its definition, severity and any associated clinical findings.
Classes of causes for night sweats:
(1) malignancy (see below)
(2) infections (see below)
(3) endocrine disorder (see below)
(4) rheumatologic disorder (see below)
(5) drugs (see below)
(6) neuropsychiatric (see below)
(7) environmental cause (see below)
(8) miscellaneous (see below)
Malignancy:
(1) malignant lymphoma
(2) leukemia or pre-leukemia
(3) hepatocellular carcinoma
(4) renal cell carcinoma
(5) other tumor
Infection:
(1) human immunodeficiency virus (HIV)
(2) mycobacteria infection
(3) infectious mononucleosis
(4) deep fungal infection (Histoplasmosis, etc)
(5) abscess
(6) endocarditis
(7) other
Endocrine disorder:
(1) diabetes insipidus
(2) ovarian failure (menopause, bilateral oophorectomy)
(3) hyperthyroidism
(4) diabetes mellitus (nocturnal hypoglycemia, autonomic dysfunction)
(5) pheochromocytoma
(6) carcinoid tumor
(7) S/P orchiectomy
Rheumatologic disorder:
(1) temporal arteritis
(2) Takayasu's arteritis
Drugs:
(1) salicylates
(2) acetaminophen
(3) antihypertensives
(4) phenothiazines
(5) substance abuse (heroin, alcohol)
(6) selective estrogen receptor modulating drugs (tamoxifen, raloxifene)
Neuropsychiatric disorder:
(1) autonomic dysfunction
(2) anxiety and/or depression
Environmental cause:
(1) excessive covers (overbundling)
(2) high room temperature
Miscellaneous:
(1) granulomatous inflammation
(2) chronic eosinophilic pneumonia
(3) Prinzmetal's angina
(4) pregnancy
(5) obstructive sleep apnea
(6) chronic fatigue syndrome
(7) gastroesophageal reflux disease
(8) lymph node hyperplasia
Specialty: Dermatology