The clinical severity of dry eye can be graded using the criteria of Marube et al. This is one of the three components of the triple classification defined at the 14th Congress of the Societas Ophthalmologica Europaea in June, 2003. The authors are from the University of Alcala in Madrid.
Patient selection: dry eye
Clinical symptoms of dry eye:
(1) feeling of dryness
(2) ocular fatigue
(3) blurry vision that disappears with blinking or use of artificial tears
(4) ocular itching
(5) photophobia
(6) blepharospasm
Clinical Features |
Description |
Grade |
diminished tear secretion without symptoms of dryness unless there is a precipitating factor (see below) |
subclinical |
1 minus |
mild symptoms |
mild |
1 |
symptomatic with reversible signs of ocular surface dryness |
moderate |
2 |
symptomatic with permanent signs of ocular surface dryness |
severe |
3 |
severe and permanent loss of vision from corneal scars, ulcerations or keratinization |
disabling |
3 plus |
Precipitating factors for symptoms of dry eye in a patient with subclinical disease:
(1) contact lens use
(2) exposure to windy weather
(3) exposure to air conditioning or a fan
(4) driving with an open car window
(5) hot weather
Reversible signs of ocular surface dryness:
(1) epithelial erosion
(2) keratopathia punctata
(3) keratopathia filamentosa
(4) ocular surface vital staining
(5) short BUT
(6) hyperemia of the exposed conjunctival trigone
Permanent signs of ocular surface dryness:
(1) corneal ulcerations
(2) nephelion
(3) leucoma
(4) corneal neovascularization
(5) epitheleal squamous metaplasia
(6) conjunctival scars
(7) retraction of the lacunar sulci
Permanent signs of ocular surface dryness
Specialty: Ophthalmology, Immunology/Rheumatology