Triphenyltin is an aryltin compound (aryl indicates an aromatic compound)
Typical use: molluscicide, rodent repellant, fungicide, anti-fouling agent
Basis for exposure:
(1) occupational
(2) intentional (suicide or homicide)
Routes of the exposure:
(1) inhalation
(2) transcutaneous
(3) ingestion
Clinical findings after a mild exposure:
(1) headache
(2) dizziness
(3) photophobia and impaired vision
(4) nausea and vomiting
(5) temporary loss of consciousness
(6) vertigo
(7) seizures
(8) dermatitis
(9) paresthesias in extremities
Laboratory findings after a mild exposure may include:
(1) transient hyperglycemia
(2) transient elevation of liver function tests
(3) elevated tin levels in blood and urine
Clinical findings after a severe exposure:
(1) prolonged loss of consciousness, usually with a delayed onset (7+ days after the exposure)
(2) peripheral neuropathy
(3) cognitive impairment affecting recent memory, calculating ability, etc.
(4) cerebellar dysfunction
(5) behavioral abnormalities (impulse control disorders)
(6) bone marrow depression
(7) nephrotoxicity
(8) more severe hepatotoxicity
(9) diarrhea or upper gastrointestinal tract bleeding
(10) impaired hearing (ototoxicity)
