Patient selection: infant with livedo reticularis which may be localized or generalized
Primary diagnostic features:
(1) The livedo does not respond to warming.
(2) There are no systemic disorders that can explain the finding.
An infant with CMTC may have one or more of the following:
(1) cardiac anomaly (patent ductus arteriosus, atrial septal defect, double aortic arch)
(2) congenital glaucoma
(3) defect in skin development (aplastic cutis, hyperplastic cutis)
(4) defect in the palate (cleft, high-arched)
(5) dental dystrophy
(6) facial asymmetry
(7) frontal bossing
(8) hypertrophy of the affected limb
(9) hypotonia
(10) macrocephaly and/or dolichocephaly
(11) macrognathia
(12) mental retardation and/or delayed motor development
(13) optic nerve atrophy
(14) seizures
(15) syndactyly
(16) vascular malformations and/or varicosities (cutaneous, cerebrovascular, Sturge-Weber syndrome)
