A patient may develop signs and symptoms during or after an infusion of infliximab. Some are minor but others can be serious or even life-threatening.
Allergic signs and symptoms:
(1) hypotension
(2) bronchospasm or wheezing
(3) urticaria
Other signs and symptoms:
(1) headache
(2) nausea
(3) fever
(4) chills
(5) dizziness
(6) flush
(7) pruritis
(8) chest and/or back pain
Time of Onset After Infusion
Reaction Timing
<= 24 hours
acute
> 24 hours
delayed
Management
Reaction Severity
admission to ICU
life-threatening
respiratory distress, hypotension, need for physiologic monitoring, admission to hospital
serious
need for extended observation usually with the need to stop the infusion
moderate
none of the above; self-limited; resolution after stopping or slowing the infusion
mild
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Specialty: Pharmacology, clinical
ICD-10: ,
