Description

Phosgene is carbonic dichloride (CCl2O) and was used as a chemical warfare agent in World War I.


 

Phosgene may be produced intentionally or accidentally. It is the byproduct of certain chemical syntheses.

 

Type of agent: choking

 

Features: colorless and denser than air (accumulates in low lying places)

 

Smell: freshly cut hay or grass

 

The initial exposure may be insidious or mildly irritating and is followed by a latency period that may range from 30 minutes to 48 hours

 

Clinical effects are dose dependent:

(1) coughing

(2) choking

(3) dyspnea

(4) hemoptysis

(5) conjunctivitis

(6) severe pulmonary edema

(7) chemical pneumonitis

(8) respiratory failure

 

Early detection can be achieved by using a specific chemical indicator badge. Exposure of a mixture of p-dimethylaminobenzaldehyde and diphenylamine to phosgene will produce a yellow to orange color.

 

Problems in diagnosis:

(1) failure to link the initial exposure with subsequent course

(2) longer duration of the latency period

(3) misdiagnosis of a regular pneumonia or asthma

(4) misdiagnosis of exposure to biological warfare agent

 


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