Description

Germann et al used classification and regression tree (CART) analysis to evaluate the risk factors associated with mortality in patients with severe burns. This can help identify patients who may require more aggressive therapy. The authors are from the BG Trauma Center (Ludwigshafen) and University of Cologne in Germany.


 

Patient selection: age range from 2 to 96 years

 

Parameters for model 1:

(1) total body surface area burned

(2) age in years

(3) alcohol abuse

total BSA

age in years

alcohol abuse

Mortality Rate

< 20%

2 – 72

NA

7%

< 20%

73 – 96

NA

67%

20 – 40%

2 – 44

NA

9%

20 – 40%

45 – 72

NA

33%

20 – 40%

73 – 96

NA

89%

> 40%

2 – 52

no

26%

> 40%

2 – 52

yes

70%

> 40%

53 - 96

NA

95%

from Figure 11, page 200

 

Parameters for model 2:

(1) abbreviated burn severity index (ABSI) of Tobiasen et al

(2) age

(3) other risk factors (alcohol abuse, inhalation injury, heart disease, smoking more than 20 cigarettes per day, female gender)

 

ABSI

age in years

other risk factors

Mortality Rate

<= 6

NA

NA

3%

7 - 10

2 – 71

affect outcome

33%

7 - 10

72 – 96

NA

70%

11 – 16

NA

NA

99%

 

where:

• The other risk factors were listed as discriminating variables with p < 0.05. However, how they impact mortality was not given.

 


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