Description

Inker et al reported equations for estimating glomerular filtration rate (eGFR) based on serum creatinine and cystatin C concentrations, age, gender and race. It was developed by the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) investigators.


 

Parameters:

(1) gender

(2) age in years

(3) serum creatinine in mg/dL

(4) serum cystatin C in mg/L

(5) race

 

Parameter

Finding

Factor A

serum cystatin

<= 0.8

-0.375

 

> 0.8

-0.711

 

 

Parameter

Finding

Factor B

gender

male

1

 

female

0.963

 

 

Parameter

Finding

Factor C

gender

male

0.9

 

female

0.7

 

 

Gender

Serum Creatinine

Factor D

female

<= 0.7

-0.248

 

> 0.7

-0.601

male

<= 0.9

-0.207

 

> 0.9

-0.601

 

 

Parameter

Finding

Factor E

race

Black

1.08

 

other

1

 

estimated GFR in mL per min per 1.73 square meter BSA =

= 135 * (((serum creatinine) / (Factors C)) ^ (Factors D)) * (((serum cystatin) / 0.8)) ^ (Factor A)) * (0.995^(age)) * (Factor B) * (Factor E)

 


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