Criteria for Symptomatic Heart Failure Associated with Adjuvant Chemotherapy

 

Parameters:

(1) clinical symptoms

(2) objective findings on the physical examination

(3) supportive evidence

 

Symptoms include:

(1) dyspnea

(2) orthopnea

(3) pedal edema

 

Objective findings:

(1) elevated jugular venous pressure (JVP)

(2) sinus tachycardia

(3) tachypnea

(4) S3 heart sound

(5) lung crackles

 

Supportive evidence:

(1) drop in LVEF by >= 10%

(2) absolute ejection fraction < 50% by MUGA or echocardiogram

(3) pulmonary edema and/or increased vascular markings on chest X-ray

 

The presence of all 3 parameters was required to diagnose subjective heart failure.