Most cases of blast crisis in a patient with chronic myeloid leukemia (CML) have blasts that mark as myeloid cells. However, other types of blasts can occur less often.
Cell Type
Findings
myeloblast
myeloid (CD33, etc)
eosinophilic blast
myeloid (CD33, etc)
basophilic blast
myeloid (CD33, etc)
monoblast
myeloid (CD33, CD14, etc)
erythroblast
CD34, CD38, CD71
megakaryoblast
CD41, CD61, Factor VIII, dysplastic platelets and megakaryocytes
lymphoblast
lymphoid (CD10, etc)
Primitive blast cells may be difficult to classify.
Sometimes the blasts may have features of more than one lineage (bilineage, other)
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