Dingli et al developed a simple scored based on the complete blood count (CBC) for evaluating a patient with agnogenic myeloid metaplasia. This can help to identify patients who may benefit from more aggressive management. The authors are from the Mayo Clinic.
Parameters:
(1) hemoglobin in g/dL
(2) white blood cell (WBC) count
(3) platelet count per microliter
Parameter |
Finding |
Points |
hemoglobin |
>= 10 g/dL |
0 |
|
< 10 g/dL |
1 |
WBC count |
< 4,000 per µL |
1 |
|
4,000 to 10,000 per µL |
0 |
|
> 10,000 per µL |
1 |
platelet count |
< 100,000 per µL |
1 |
|
>= 100,000 per µL |
0 |
where:
• The cutoff for hemoglobin was not adjusted for gender.
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 3
• The higher the score the lower the median survival.
Total Score |
Median Survival |
0 |
155 months |
1 |
69 months |
2 or 3 |
24 months |
Additional risk factors associated with reduced survival:
(1) presence of constitutional symptoms (night sweats, unexplained fever > 100°F, unintended weight loss > 10% of baseline body weight)
(2) hepatomegaly
Specialty: Hematology Oncology
ICD-10: ,