Description

The Renal Fanconi Syndrome (RFS) can be caused by a large number of factors.


 

Inherited conditions:

(1) cystinosis

(2) cytochrome C oxidase deficiency

(3) Dent's disease

(4) galactosemia

(5) glycogen storage disease type I

(6) hereditary fructose intolerance

(7) oculocerebrorenal syndrome (Lowe's syndrome)

(8) tyrosinemia type I (hepatorenal)

(9) vitamin-D dependent rickets

(10) Wilson's disease

 

Toxic:

(1) heavy metals (lead, cadmium, mercury, uranium)

(2) toluene

(3) tributylin oxide

(4) Lysol

(5) methyl-3-chromone

(6) paraquat

(7) nitrobenzene

 

Drug-related:

(1) 6-mercaptopurine

(2) caphalothin

(3) gentamicin

(4) ifosfamide

(5) salicylates

(6) tenofovir

(7) tetracyclines that is outdated

(8) valproic acid

 

Renal conditions

(1) nephrotic syndrome

(2) interstitial nephritis with antibodies to the tubular basement membrane

(3) renal transplant

 

Malignancy-related:

(1) cancer

(2) Bence-Jones protein in multiple myeloma

 

Some cases may be idiopathic.

 


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