Cardiometabolic Disease Staging System (CMDS)

Description

Guo et al reported the Cardiometabolic Disease Staging System (CMDS). This can monitor an obese patient over the spectrum of cardiometabolic disease and can predict future cardiovascular disease. The authors are from the University of Alabama at Birmingham.

Parameters:

(1) number of risk factors (from 0 to 4)

(2) fasting glucose

(3) 2-hour glucose tolerance

(4) active cardiovascular disease (angina pectoris, S/P acute coronary artery syndrome, S/P coronary artery stent placement, S/P coronary artery bypass graft surgery, S/P thrombotic stroke, S/P peripheral arterial disease with non-traumatic amputation

Risk factors:

(1) increased waist circumference for gender (>=112 cm male, >=88 cm female)

(2) elevated blood pressure (any of the following: systolic >= 130 mm Hg, diastolic >= 85 mm Hg, on antihypertensive medications)

(3) low serum HDL-cholesterol for gender (any of the following: < 40 mg/dLor < 1 mmol/L for male, < 50 mg/dL or < 1.3 mmol/L in female, on medication)

(4) elevated fasting serum triglycerides (>=150 mg/dL or >= 1.7 mmol/L, on medication)

The Metabolic Syndrome is present when 3 or 4 of the risk factors are present.

Fasting Glucose	Interpretation
< 100 mg/dL (< 5.6 mmol/L)	not impaired
100 to 125 mg/dL	impaired
>= 126 mg/dL	type 2 diabetes mellitus

2-Hour Glucose Tolerance	Interpretation
<= 139 mg/dL (< 7.8 mmol/L)	not impaired
140 to 199 mg/dL	impaired
>= 200 mg/dL	type 2 diabetes mellitus

Risk Factors	Fasting Glucose	Glucose Tolerance	CVD	Stage
0	normal	normal	absent	0
1 or 2	normal	normal	absent	1
3 or 4	normal	normal	absent	2
<= 2	impaired	normal	absent	2
<= 2	normal	impaired	absent	2
3 or 4	impaired	NA	absent	3
3 or 4	NA	impaired	absent	3
NA	impaired	impaired	absent	3
NA	diabetes	NA	NA	4
NA	NA	diabetes	NA	4
NA	NA	NA	present	4

Stage	Odds Ratio CVD
0	1
1	3.6
2	5.7
3	5.7
4	14.6

adjusted for important confounders

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Description

Specialty

Objective

ICD-10

Cardiometabolic Disease Staging System (CMDS)

Purpose: To stage an overweight patient for the cardiometabolic syndrome using the CMDS of Guo et al.

Description

Specialty

Objective

ICD-10