Chow et al listed endpoints for therapy used to relieve pain associated with bone metastases.
Parameters:
(1) current pain score (from 0 to 10)
(2) difference between current and baseline pain scores
(3) ratio of current analgesic daily dose to baseline pain dose, using oral morphine equivalent dose (OMED)
difference between pain scores =
= (baseline pain score) - (current pain score)
ratio of analgesic dose =
= (current dose) / (baseline dose)
|
Pain Score |
Change in Pain Score |
Analgesic Dose Ratio |
Response |
|
0 |
NA |
0 |
<normal> |
|
0 |
NA |
<= 1.00 |
complete |
|
NA |
>= 2 |
<= 1.00 |
partial |
|
NA |
>= 0 |
<= 0.75 |
partial |
|
NA |
<= -2 |
1.00 |
progression |
|
NA |
0 or -1 |
>= 1.25 |
progression |
Any pattern not described in the above table is considered stable pain.
A responder is a person with a complete or partial response. Any other pattern indicates a nonresponder.
Purpose: To determine the response to therapy intended to control pain.
Specialty: Sports Medicine & Rehabilitation
Objective: criteria for diagnosis, severity, prognosis, stage, response to therapy
ICD-10: C79.5, R52.1, R52.2,
