Allawadhi et al used the extent of bone marrow involvement seen on magnetic resonance imaging (MRI) to stage patients with multiple myeloma. MRI is a sensitive and noninvasive method to determine myeloma tumor burden. The authors are from Roswell Park Cancer Institute in Buffalo.
Parameters:
(1) total area of bone marrow evaluated by MRI
(2) area of bone marrow involved by myeloma on MRI
percent involvement =
= (area of bone marrow involvement) / (total area examined) * 100%
Percent Bone Marrow Involvement
Stage
0%
A
0.1 to 9.9%
B
10 to 50%
C
> 50%
D
Stage
10 Year Survival
A or B
91%
C or D
58%
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