Description

The Biopharmaceutical Classification Scheme (BCS) classifies a drug based on its solubility and permeability characteristics.


 

Parameters:

(1) solubility

(2) permeability

 

Solubility

Permeability

Class

high

good

1

low

good

2

high

poor

3

low

poor

4

 

where:

• One modification would be to expand the choices to include intermediate solubility and fair permeability. This would result in 9 combinations.

 

Class

Potential Bioavailability After Oral Dosing

1

excellent

2

good to fair

3

fair

4

poor

 


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