Strontium-89 is taken up by bone and can be used to palliate bone pain in patients with metastatic tumors. The simple clinical score can be used to assess the effectiveness of the treatment .
Patient selection:
(1) patients with bone metastases to more than 1 site
(2) pain no longer responsive to conventional therapy
(3) life expectancy of at least 3 months
|
Parameter |
Finding |
Points |
|
general condition |
deteriorated |
-1 |
|
|
unchanged |
0 |
|
|
some improvement |
+1 |
|
|
definitely better |
+2 |
|
mobility |
more restricted |
-1 |
|
|
essentially unchanged |
0 |
|
|
less restricted |
+1 |
|
analgesics |
quantity increased |
-1 |
|
|
essentially unchanged |
0 |
|
|
quantity decreased 20-45% |
+1 |
|
|
quantity decreased 50-80% |
+2 |
|
|
analgesics virtually discontinued |
+3 |
|
pain analysis |
at least 1 point increase in the majority of affected sites |
-2 |
|
|
about 1 point increase in some sites |
-1 |
|
|
no change in most sites |
0 |
|
|
about 1 point decrease in some sites |
+1 |
|
|
at least 1 point decrease in the majority of affected sites |
+2 |
where:
• pain was recorded on a 5 point scale
total score =
= (points for general condition) + (points for mobility) + (points for analgesics) + (points for pain analysis)
Interpretation:
• minimum score: -5
• maximum score: +8
|
Total of Scores |
Overall Assessment |
|
-5, -4, -3, -2 |
deteriorated |
|
-1, 0, +1 |
no significant change |
|
+1, +2, +3 |
some improvement |
|
+4, +5, +6 |
substantial improvement |
|
+7, +8 |
dramatic improvement |
Specialty: Hematology Oncology
ICD-10: ,
