Description

The American Thoracic Society (ATS) has developed criteria for determining the level of impairment experienced by a patient with asthma. This can be used to monitor a patient and to evaluate the response to interventions.


 

Parameters:

(1) post-bronchodilator FEV1 relative to predicted value

(2) change in FEV1 (reversibility) OR airway hyperresponsiveness

(3) minimum medication needed

 

Parameter

Finding

Points

post-bronchodilator FEV1

> lower limit of normal

0

 

70% to lower limit of normal

1

 

60 – 69%

2

 

50 – 59%

3

 

< 50%

4

reversibility of FEV1 OR airway hyperresponsiveness

FEV1 change < 10%, OR

PC20 > 8 mg/mL

0

 

FEV1 change 10 - 19%, OR

PC20 0.51 to 8 mg/mL

1

 

FEV1 change 20 - 29%, OR

PC20 0.126 to 0.50 mg/mL

2

 

FEV1 change >= 30%, OR

PC20 <= 0.125 mg/mL

3

minimum medication

none

0

 

occasional bronchodilator, not daily; occasional cromolyn, not daily

1

 

daily bronchodilator; daily cromolyn; low dose inhaled steroid

2

 

bronchodilator on demand and daily high dose inhaled steroid or occasional course of systemic steroids

3

 

bronchodilator on demand and daily high dose inhaled steroid and daily systemic steroids

4

 

where:

• Low dose inhaled steroid is < 800 µg beclomethasone or equivalent.

• High dose inhaled steroid is >= 800 µg beclomethasone or equivalent.

• Occasional course of systemic steroids involves 1 to 3 courses per year.

• percent FEV1 change = 100% * (((FEV1 post-bronchodilator) / (FEV1 prebronchodilator)) – 1)

• The calculation for PC20 (as a measure of airway responsiveness to methacholine or histamine) is given in the pulmonary chapter.

 

impairment score =

= SUM(points for the 3 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 11

 

Score

Impairment Class

0

0

1, 2 or 3

I

4, 5 or 6

II

7, 8, or 9

III

10 or 11

IV

asthma not controlled despite maximal treatment

V

 

where:

• Asthma not controlled despite maximal treatment = FEV1 < 50% despite prednisone dosing at >= 20 mg/day.

 


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