Cardiotoxicity is a therapy-limiting toxicity with anthracyclines. Keefe compared the cardiotoxicity of various anthracyclines. The author is from Memorial Sloan Kettering Cancer Center in New York City.
Anthracycline
Dose with 5% Cardiotoxicity
Conversion Factor
daunorubicin
900 mg per square m
0.5
doxorubicin
450 mg per square m
1
epirubicin
935 mg per square m
0.5
idarubicin
225 mg per square m
2
mitoxantrone
200 mg per square m
2.2
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