Assay: serum alpha-fetoprotein (AFP)
Cutoff for automated dilution: 200 ng/mL
Cutoff for manual dilution: > 5,000 ng/mL
Parameters:
(1) history of past AFP results
(2) current assay result
The specimen is reported directly if:
(1) there is no history of a previous AFP AND the current result is <= 200 ng/mL
(2) the previous AFP was <= 200 ng/mL AND the current result is <= 200 ng/mL
The specimen is sent for automated dilution if:
(1) there is no history of previous AFP AND the current result is > 200 ng/mL
(2) the previous AFP was <= 200 ng/mL AND the current result is > 200 ng/mL
(3) the previous AFP was > 200 and <= 5,000 ng/mL
The specimen is sent for manual dilution if:
(1) the previous AFP was > 5,000 ng/mL
(2) a result with automated dilution is > 5,000 ng/mL
