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Risk Factors for Early Death Following Conventional Chemotherapy

Purpose: To evaluate a patient who is starting chemotherapy for risk factors associated with early death based on the report of Ray-Coquard et al.

Description

Ray-Coquard et al identified risk factors associated with early death following chemotherapy for a solid tumor or malignant lymphoma. This can help to identify a patient who may benefit from closer monitoring and more aggressive management. The authors are from multiple hospitals in France who participate in the ELYPSE Study Group.


Patient selection: starting conventional cancer chemotherapy

 

Outcome: early death (death within 31 days of receiving chemotherapy)

 

Parameters:

(1) WHO/ECOG performance status (PS)

(2) absolute lymphocyte count

 

Parameter

Finding

Points

performance status

0 or 1

0

 

2, 3 or 4

1

absolute lymphocyte count

> 700 per µL

0

 

<= 700 per µL

1

 

number of risk factors =

= SUM(points for both risk factors)

 

Interpretation:

• minimum score: 0

• maximum score: 2

• The higher the score the greater the risk of early death.

 

Score

Percent Early Death

0

1.7%

1

6%

2

20%

 


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Specialty

Objective

ICD-10