Description

A pediatric patient with an adrenocortical tumor may experience a combination of Cushing's disease, precocious puberty and/or virilization.


 

Clinical features related to the tumor itself:

(1) palpable abdominal mass

 

Clinical features related to excess glucocorticoids:

(1) buffalo hump

(2) moon face

(3) centripetal fat distribution

(4) hypertension

(5) weight gain

 

Clinical features of androgenic steroids:

(1) pubic hair

(2) clitoral or penile hypertrophy

(3) acne

(4) deep voice

(5) facial hair

(6) hirsutism

(7) accelerated growth velocity

 


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